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박진희 ( Park Jin-Hee ) - 아주대학교 간호대학
정용식 ( Jung Yong-Sik ) - 아주대학교 의과대학 유방외과
김지영 ( Kim Ji-Young ) - 아주대학교 의과대학 유방외과
배선형 ( Bae Sun-Hyoung ) - 아주대학교 간호대학
조유정 ( Jo Yu-Jung ) - 아주대학교 간호대학
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Abstract
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Purpose: The aim of this study was to evaluate the severity of menopausal symptoms and their impact on the quality of life (QOL) in breast cancer patients with chemotherapy-induced amenorrhea.
Methods: A cross-sectional survey design was used. Participants were 112 breast cancer patients with chemotherapy-induced amenorrhea. They completed the Menopause Rating Scale (MRS) and the Functional Assessment of Cancer Therapy-General (FACT-G). Data were analyzed using descriptive statistics, independent ttests, one-way ANOVA, Pearson’s correlation coefficients, and multiple regression with SPSS/WIN 23.0.
Results: The prevalence of symptoms among the participants were as follows: sleep problems, 88.4%; physical and mental exhaustion, 80.4%; joint and muscular discomfort, 76.8%; and depression, 70.5%. Menopausal symptoms had a significant negative association with QOL. The results of the regression analysis showed that psychological and urogenital symptoms were statistically significant in explaining patients’ QOL and accounted for 70% of the total variance.
Conclusion: Menopausal symptoms appear to be a significant problem for premenopausal breast cancer patients. Assessment and control of menopausal symptoms played a large role in maintaining the quality of life in breast cancer patients.
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KeyWords
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유방암, 갱년기, 삶의질, 항암화학요법
Breast neoplasms, Menopause, Quality of life, Drug therapy
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원문 및 링크아웃 정보
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등재저널 정보
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